Publishing their work in Nature, scientists at the UNC School of Medicine and UNC Gillings School of Global Public Health tested how the orally administered experimental drug EIDD-2801 halts SARS-CoV-2 replication and prevents infection of human cells in a new in vivo model containing human lung tissue.
They found that the drug was extremely effective and preventing and treating SARS-CoV-2 infection. Phase 2 and 3 clinical trials are ongoing to evaluate EIDD-2801 safety in humans and its effect on viral shedding in COVID-19 patients.
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EIDD-2801 is expected to cause birth defects in pregnant women