"These findings are the result of five years of work stemming from a long-standing collaboration between my lab and Dr. Claire Chougnet's lab, contributions from several faculty-level scientists, and particularly the hard work of one amazing former graduate student, Dr. Maha Almanan," Hildeman says.
The detectives ultimately traced excess IL-10 production to the cell type they dubbed Tfh 10. Then, in mouse models, they showed that simple blockade of IL-10 at the time of vaccination could restore the antibody response nearly to the level of young animals
