Hoge said three things needs to happen before Moderna applies to the FDA for emergency use authorization.
Of the 30,000 participants, 53 need to become sick with Covid-19. The company expects that to happen in the second half of November.
The second milestone is that of the 53 participants who become ill with Covid-19, at least 40 of them need to be participants who received the placebo. That would show the vaccine is 75% effective.
The third milestone is a requirement by the FDA to ensure that enough time has passed to see if participants develop side effects. The FDA rule is that at least eight weeks must pass after half the participants have received their second shot before a company can apply for emergency use authorization.