Ming-Jim Yang, M.D., from the University of Florida in Gainesville, and colleagues conducted a retrospective review involving 2,005 patients older than 18 years of age who tested positive for COVID-19. Influenza vaccination status and comorbidities were examined. Severity of disease as reflected by hospitalization and intensive care unit (ICU) admission was examined as the primary outcome. The association between influenza vaccination status and hospitalization was examined.
The researchers found that compared with those who were vaccinated, COVID-19-positive patients who had not received the influenza vaccine within the last year had 2.44- and 3.29-fold increased odds of hospitalization and ICU admission, respectively. The results were adjusted for age, race, gender, hypertension, diabetes, chronic obstructive pulmonary disease, obesity, coronary artery disease, and congestive heart failure.
