COVID-19 may deplete testosterone,
helping to explain male patients' poorer prognosis

https://medicalxpress.com/news/2020-09-covid-deplete-testosterone-male-patients.html

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Testosterone is associated with the immune system of respiratory organs, and low levels of testosterone might increase the risk of respiratory infections. Low testosterone is also associated with infection-related hospitalization and all-cause mortality in male in ICU patients, so testosterone treatment may also have benefits beyond improving outcomes for COVID-19," Professor Çayan explains.

"In our study, the mean total testosterone decreased, as the severity of the COVID-19 increased. The mean total testosterone level was significantly lower in the ICU group than in the asymptomatic group. In addition, the mean total testosterone level was significantly lower in the ICU group than in the Intermediate Care Unit group. The mean serum follicle stimulating hormone level was significantly higher in the ICU group than in the asymptomatic group.

"We found hypogonadism—a condition in which the body doesn't produce enough testosterone—in 113 (51.1%) of the male patients.

"The patients who died, had significantly lower mean total testosterone than the patients who were alive.

"However, even 65.2% of the 46 male patients who were asymptomatic had a loss of loss of libido."

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