In my real-quick-read here of this topic ...one quick point someone raised before that was not discussed and thought of more seriously.....

That is water-injection.

Using W I ... you can go way leaner in the A/F ratio, put more timing in the motor and use more compression ratio. ..... BUTTTTT ...don't EVER run it out-of-water !

I had a long-ago project(truck/camper/trailer combo) that I did using an old Spearco system that helped a BUNCH but I did not flog-it-out as much as I would have liked to. But now ... I have a vintage Dodge motorhome that I DO want to "flog" this out on now ... as the price of gas is alot diff than back in those days.

More later ... if anyone is interested.