Monte...the more plenum volume the better w/ nitrous? Cast single 4500 manifold in question.

I experimented w/ an Indy 426-4 manifold in the past on my hemi. It's a good bit larger in both the plenum and runners than my Barton manifold. It hurt the lowend grunt significantly naturally aspirated, but I'm thinking it may be the way to go w/ nitrous?

CHIP
'70 hemicuda, 575" Hemi, 727, Dana 60
'69 road runner, 440-6, 18 spline 4 speed, Dana 60
'71 Demon, 340, low gear 904, 8.75
'73 Chrysler New Yorker, 440, 727, 8.75
'90 Chevy 454SS Silverado, 476" BBC, TH400, 14 bolt
'06 GMC 2500HD LBZ Duramax