IMHO, I would think it would be less than ideal. Placing all the injectors accurately so they shoot at the back of the intake valve is tricky because of the shape of the runners.

A DP wet flow manifold is a compromise to assure good air velocity at low engine speeds so the carb gets good signal and the engine sees decent fuel distribution.

A port injected engine doesn't have this problem to deal with so a single plane doesn't give up anything on the bottom as all it has to do is deliver air. Runner shape makes ideal injector location easier too.