Usually pretty easy once you are within your max rpm/trap afr's by within a point then if it's rich up top bigger hi bleeds, lower float levels and even mixture screws balance that out. I have a NMCA HEMI super stocker that runs 2 1000 cfm billet 4150's and was at a race where the air got real good in the later part of the day and went from the desirable 12.9-13.1 to 13.7 and lost mph and et plus was in the lanes for the final race so I had him open up all 8 mixture screws and it was right back at 13.1 up top but he red lit and lost the race because it reacted quicker and cleaner. Emulsion placement and sizes is yet another way.......Who needs EFI when a wet manifold has been proven to make more power over and over again....