Yes Acetone and Xylene will both increase octane, cool the mixture and increase efficiency the burn by streaching out the carbon links to the hydrocarbons and allow more inflitration of the Oxygen, if you really want add 1-25 OXYGEN GAS ALSO AND IT WILL BRING THE AEDIBATIC HEAT OF COMBUSTION WAY UP AND THEREFORE MORE POWER PER GIVEN VOLUME OF INTKE CHARGE. ALL OTHER THINGS BEING EQUAL. 10% ALCOHOL AND 5% ACETONE AND 5% XYLENE MAKES A NICE BREW YOU CAN BUBBLE XYLENE THROUGH GLYCRINE AND NITRIC ACID AND BREW YOUR OWN LOW END NITROMETHANE AND MIX 10% with the gas.
acetone, alcohol , xylene and nitric acid and glycerine all cost way more than plain hightest so the gains would be a wash out cost wise and also try to avoid blowing yourself up.
ive been bubbling octane through Hudrogen gas and forming a solid tri hydrogen octane solid which will give off gas when inmmersen in hydrogen peroxide and provide the free oxygen to burn the Hydrogen, but I dont recommend you kids try this at home . it releases power beyond what a compressed CNG cylinder can hold (boom)

but does rrun a lawnmowner on water and peroxide from the drug store.