Yes you can but it isn't recommended. The MSD uses an inductive pickup and EFI systems really prefer a nice square wave trigger. So all of the EFI vendors recommend using Hall effect triggers. The Hyperspark has a Hall effect pickup in it and it is already locked out.

I sold my MSD to a guy who wanted a MSD billet distributor and took the cash and bought the Hyperspark. The Hyperspark distributor is fairly inexpensive since it is just a housing with a spinning target wheel and a trigger pickup.

If you have a MSD I'd recommend doing the same thing. Sell it rather than try to convert it and buy the Hyperspark.