I was planning on going with a megasquirt multiport injection setup on my 440 Ramcharger. (DaytonaTurbo )

I think everyone has a particular set of reasons or requirements that would cause them to choose one over the other.

My list of things is:

Driveability
System feedback
Ignition control (power/cruise/economy modes)
Modern "feel"
No need to "keep in tune".

I also have to take into consideration that this truck is my daily driver and also a vehicle that will be used for camping. My current elevation is roughly 1200' AMS, and I could potentially drive in a couple of hours and be pushing close to 7000' AMS. That's not always the best circumstances for running a carb.