The only lifters I will ever run are those suggested by the cam manufacturer. I am not a metallurgist. I run almost all flat tappet cams ( soild and hyd). I run a quality synthetic oil with zinc. I make sure the lifter bores and lifters are perfectly clean ( lifter bore drop test). I rotate the engine by hand with the intake off to make sure all lifters are rotating. I don't have compatibility problems and I don't have flat tappet cam failures.