if the distributor has never been in yet, then this is no issue. you still have to get it in and set it to an approximate initial timing. this needs to be done regardless, so there is nothing you need to do with this first. prime, and then set your distributor timing as normal.

to prime, you need a beefy 1/2" drill. have the plugs out and have someone rotate the engine a couple of times while you are doing it. that can be a good time to make sure oil is getting to both cylinder heads as well, as through rotating the engine, you will expose the head oiling passages in the #4 cam bearing.