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I think it would be simpler to do a 4" stroke engine. More cubic inches need more head and even with the heads you have a 4" stroke engine will easily max those heads out.

You need to look at piston speed & rod ratio too , We have run 3.79 & 4" cranks in our W5 LA rig , I think the 3.79 over all is the better stroke , But we like to turn it up a bit to make power