I'd call Patrick and get you a tweaked Pro-Systems 1000hp 4150, I have 2 of them (one on my 517BB and one on my 414SB) and they are night and day over an OOTB unit for not much more $$$.

As said the 2.19 will tend to pick up the mid range and on a big block they would typically have a similar effect on torque to running a 4-8 degree larger @.200 duration cam. The gains on a conventional height BB port tend to be limited by the short turn and low runner height, not to mention the relatively poor valve to piston wall (shrouding) clearance, so a bigger valve doesn't always help as much (% gain) on a BB standard port head as you might see with a raised port Max Wedge.

I've run 2.25's in an old set of 67' 915's but it was tight and if I didn't notch the bores I doubt it would have helped at all over a 2.19.