What cam went 12.25? Exhaust manifolds or headers? And what mufflers?

What are the full cam specs now, and what mufflers are you running? What is the displacement?

250* at .050 with pretty much any ICL or LSA is probably too much for exhaust manifolds, let alone in a 9.3:1 engine. That does not sound like a cam spec’d for manifolds at all.

I think your exhaust manifolds and the turbo mufflers you’re probably running (especially if they are Hush Thrush) are killing a lot more power than you think. And the 250* cam put a big hole in the torque curve and you’re hitting your converter way less than the old combo did, which is exacerbating the issue.