All I can add is the pump-gas 499 440-1 engine that Herb McCandless & Co. built for the '95 Hot Rod Pump-Gas Big-Block Challenge ran a Cam Motion roller that spec'd 276/281 @ .050" w/ 110 LSA installed on 106 ICL. Lift was well over .700" w/ 1.7 Jesel rockers. McCandless didn't even care about quench then and ran flat-top pistons "way down" in the hole (something like .075" or .100", IIRC) w/ only 9.5 CR.

One of the tricks about that engine was that it had a lot of epoxy in the heads and manifold which were used to reduce the intake runner sizes and keep up the velocity. Too bad they didn't give either flow #s or runner cc sizes for those heads.