In one of my 440s I ran an Engle hydraulic FT dual-pattern, about 234/244 @ .050 and a bit over .500 lift.
Great manners, a bit healthier than stock, very tractable with 4-speed & fairly tall final gear.
Also ran the EDM lifters (oiling hole), 1.5 roller rockers, 10.2 CR with Eddy heads, Maxie manifolds & full exhaust.
Just avoid the long-duration stuff.