I assume you are talking about the 108 LSA version. I think to answer this question we would have to know more about your setup.

Just as a point of reference, I have this cam (108LSA version) in a 416 SB stroker and I have power brakes and it works fine. I get about 14" of vacuum idling at 900-950rpms.

Your results will vary depending on your setup. I don't have AC so I can't comment on how this cam will work with AC. Others will have to chime in on that.