Talking about a 600 hp application:

IMO the biggest benefit in a turbo application is the ability to run a much more numerically lower gear than a N/A motor.

Also, I don't think an N/A motor with a fairly healthy cam is going to be as efficient at lower speeds than a relatively "stock" cam that a turbo uses.

Finally, a stock type converter can be used vs a higher stall of an NA application.