Not the first detonation engine powered USA weapon.
https://airandspace.si.edu/stories/editorial/buzz-bomb-70th-anniversary-v-1-campaignsample quote
The V-1 (Buzz Bomb of Germany) had an interesting afterlife in the United States.
In a rare American example of outright copying, the Army Air Forces and the Navy decided to mass produce a version for the attack on Japan.
By the end of 1944, the first copy,
which went by the AAF designation JB-2 (Jet Bomb 2) was launched from Eglin Field in Florida out over the Gulf of Mexico.
After World War II suddenly ended in August 1945, mass production was stopped, but the U.S. Navy continued to use its version, called the Loon,
to gain experience with firing missiles from ships and submarines. It was a precursor to larger, nuclear-armed cruise missiles like the Regulus the Navy deployed in the 1950s.