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I searched for an hour on here and found many references to offset boring of cylinders (side to side....not front to rear) to compensate for block core shift, but nowhere did I find what might be considered an acceptable (or maximum) amount of offset. Are there considerations other than the combustion chambers? Thanks.

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I'm running a 71 360 block with one hole offset bored with no problem. Wasn't done for core shift though. Had some detonation problems with a 408 motor that was already .030 over. Broke a top ring land and did minor bore damage. Had the hole bored for a .040 over slug to fix the damage ( .009 on the damaged side and .001 on the good side. Worked great. I guess I'm one of the few guys that is running a 410 ( or there abouts ) stroker motor. . If I remember, the damage was towards the front of the block, but I would guess you could easily get away with that much offset ( and probably more) anywhere 360 degrees in the hole.