Here is a short video of a 700 hp 505 that I helped put together. This engine has TF270 heads and is 11:1 compression so very close to what you describe. It was too radical for a manual transmission so the owner had to swap in a 727 with a high stall converter. I think you'll have the same problem if you use that large of a camshaft. You won't be able to drive the car on the street since you won't have enough torque right off idle to leave a stop light.
https://youtu.be/fGiFuOuBnvQRunning a hyd roller isn't a problem, I use them all the time in BB Mopar engines. But if you are going to street drive it with a 5 speed overdrive transmission then you'll need to keep the cam size down into the 240 or maybe 250 range. I use a 239/245 hyd roller in my '65 Coronet and it is a tad too big for really comfortable street driving with a 5 speed manual transmission. My car would be more comfortable with lobes that were one size smaller. My engine has TF240 heads and makes a little over 600 hp.
