If it were me I'd avoid staying in big cities. Make the hotel the only stop in the area, in other words don't stop for dinner at the diner across the street from the hotel, Bring a car cover and cover it immediately upon arrival. If there are rooms at the back of the hotel, take one of those so the car is as out of sight as possible. Consider something to disable the car each night - like removing the battery. Just consider your options and you should be fine. Personally I think a car standing on its own is far safer than one all loaded up on a truck and trailer just screaming "steal me". The worst I ever had happen years ago was someone stole my tire valve caps !!