Have been using e85 for around 8 years and have had no issues with engines being hurt etc. We did run into some issues with BarryGrant fuel pressure regulators eating the seat. Have run Aeromotive, holley, magna fuel and quick fuel products and have had no issues.

It is a great alternative race fuel. Requires a little more maintenance than gas but not nearly what you would do with methanol. The big advantages are cooler temps, cost and it makes more power.