Your combo is close to my old combo and real close to my new.
My old combo was .030 over 383, 9.4:1, solid flat 250@.050 .580 lift, 1.6 ratio, ported 906, 2" headers, 5800 stall. This combo was modeled after the 500HP 383 Dwayne (Fast69Plymouth) did that is detailed in the tech archives.
http://www.moparts.org/Tech/Archive/bb/25.html If you have a 383 there is a lot of really good information in those two threads, definitely worth the read.
Last year I tried lots of intakes and carb on my old combo. I have an RPM, TM6, Victor 383, M1 4500, Holley SD, Torker, and tunnel ram. For carburetors I have run everything from a Demon 750 all the way to a 1050 Dominator. My TM6 has had the dimples welded up and the top blended into the runners and it has proven to be the fastest on my car (3400lbs Duster). I did also use a phenolic 2" merge spacer and would say that with all the intakes a spacer most always helped, especially on the RPM. A 2" merge spacer on the RPM was a noticable difference (picked up the front wheels). My best carb has been an 4150 QF 950 Annular booster (v1.450/tb1.750), so don't be afraid to carb up, especially since you have some decent compression. The only thing I noticed with a larger carb is it requires more tuning. The 4500 2 circuit on the RPM was also a good combo using a HVC 2" adapter. On my car, I lost 2 mph when I put some exhaust on it from open headers. What I have described above is with a 3.5" exhaust (race muffler and extension to rear tires). I kept adding timing and it kept getting faster, I finally quit at 40 degrees. In the summer I will dial it back to 38 ( dist is locked out). I shifted at 6000 1-2, 6500 2-3, 6800 through the traps.
If are over 3500lbs and have room for a spacer, I would likely suggest the RPM with a 2" merge spacer with an 850 or larger annular booster carb. The dual plane seems to like the annular booster and an annular booster tends to do better with a larger venturi (+1.450). You will need a fairly high stall converter and a decent gear to really make it work.
