Re: The official Coronavirus thread
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#2807286
08/10/20 02:02 PM
08/10/20 02:02 PM
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British researchers claim they will soon have a blood test that predicts who may get severe Covid-19 https://medicalxpress.com/news/2020-08-scientists-unique-molecular-signature-blood.htmlSample quote The researchers analyzed over 100,000 blood samples from the UK Biobank and identified a particular molecular signature in the blood that's common among people who get severe symptoms if infected by the coronavirus. Those with this molecular signature are five to 10 times more likely to be hospitalized. These findings are novel, as the blood biomarkers in the molecular signature have not been previously known as risk markers in healthy people for developing severe forms of COVID-19. This is the world's largest metabolomic study to date and based on the study's findings Nightingale Health is soon launching a blood test that can predict if a person will develop mild symptoms or become severely ill due to COVID-19. The test can, therefore, be used to identify people who'll need special precautions to avoid infection and prioritize those in most need of the COVID-19 vaccine. End quote
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Re: The official Coronavirus thread
[Re: 360view]
#2807288
08/10/20 02:09 PM
08/10/20 02:09 PM
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Joined: Jan 2006
Posts: 8,162 USA
360view
Moparts resident spammer
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Moparts resident spammer
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USA
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Re: The official Coronavirus thread
[Re: 360view]
#2807290
08/10/20 02:13 PM
08/10/20 02:13 PM
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Moparts resident spammer
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What heart disease patients need to know about Covid-19 https://medicalxpress.com/news/2020-08-heart-patients-covid-.htmlSample quote Data released in June by the Centers for Disease Control and Prevention shows COVID-19 patients with underlying conditions such as cardiovascular disease are six times more likely to be hospitalized and 12 times more likely to die than patients without any chronic health problems. About 1 in 3 people with COVID-19 has cardiovascular disease, making it the most common underlying health condition. End quote
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Re: The official Coronavirus thread
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#2807725
08/11/20 02:48 PM
08/11/20 02:48 PM
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2 new trials of manufactured antibodies https://medicalxpress.com/news/2020-08-covid-network-monoclonal-antibodies.htmlSample quote The COVID-19 Prevention Network (CoVPN) today announced two Phase 3 trials to determine whether monoclonal antibodies (mAbs) can prevent SARS-CoV-2, the virus that causes COVID-19. The first trial, CoVPN 3501, will evaluate LY-CoV555, an Eli Lilly and Company mAb to see whether it can prevent SARS-CoV-2 infection among people living or working in skilled nursing and assisted living facilities. Scientists from the National Institute of Allergy and Infectious Diseases Vaccine Research Center and Abcellera Biologics discovered LY-CoV555. The trial will enroll up to 2,400 participants in the U.S. who will be randomized to receive an intravenous infusion of LY-CoV555 or a placebo. The second trial, CoVPN 3502, will evaluate REGN-COV-2, a Regeneron Pharmaceutical double mAb combination, to see if it will prevent infection among household contacts with close exposure to someone recently diagnosed with COVID-19 that has been sustained for at least 48 hours. The study will enroll approximately 2,000 participants in the U.S. End quote
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Re: The official Coronavirus thread
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#2807730
08/11/20 02:57 PM
08/11/20 02:57 PM
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Joined: Jan 2006
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Moparts resident spammer
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Moparts resident spammer
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Re: The official Coronavirus thread
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#2807816
08/11/20 07:07 PM
08/11/20 07:07 PM
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Moparts resident spammer
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Moparts resident spammer
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Re: The official Coronavirus thread
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#2807959
08/12/20 08:18 AM
08/12/20 08:18 AM
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Joined: Jan 2006
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Moparts resident spammer
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Sweden was hoping for Covid-19 “herd immunity” of 60% by now, instead 15% of population Presently tested have antibodies to Covid-19. https://medicalxpress.com/news/2020-08-covid-herd-immunity-sweden-materialize.htmlArticle does not state it, but perhaps another 15% have T-cell immunity, and another 15% are protected by “common cold coronavirus” past infections? The sad thing is that Sweden has admitted that their Nursing Home fatalities were allowed to die at the Nursing Homes with little treatment. Very few were taken to ICU’s at hospitals.
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Re: The official Coronavirus thread
[Re: 360view]
#2808118
08/12/20 02:41 PM
08/12/20 02:41 PM
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3 months ago French said “Do not take Ibuprofen/Motrin if you suspect you might have Covid-19.” Now British researchers say they find “no strong evidence” that taking Ibuprofen, Naproxen sodium (Aleve) or Diclofenac (Voltaren) leads to any greater Covid-19 fatality rate. https://medicalxpress.com/news/2020-08-ibuprofen-death-covid-.html
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Re: The official Coronavirus thread
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#2808120
08/12/20 02:51 PM
08/12/20 02:51 PM
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A year 1990 study in soldiers suggested that T-cells remain protective for about one year after catching one of the four coronaviruses that circulate as what we call “the common colds”. https://medicalxpress.com/news/2020-08-coronavirus-common-cold-covid.htmlSample quote The findings raised concern that SARS-CoV-2 could infect a person many times and that a vaccine might not generate lasting protection. But the article focused on just one arm of the immune response, the B cells, which produce antibodies that help to clear an infection. T cells are also key to the immune response against viruses. They play a variety of roles, among them helping B cells to mature into disease-fighting machines. The article by Jose Mateus and colleagues at La Jolla Institute for Immunology is important because it shows that people keep T cells from the milder coronaviruses long enough to potentially interact with a new challenge by SARS-CoV-2 and that those T cells might even recognize SARS-CoV-2 and help to clear the infection. ...snip... The milder coronaviruses can generate similar antibodies to the ones that are generated by the coronaviruses that cause SARS and Mers. These antibodies are so similar that they nearly tricked a British Columbia care facility into thinking they had an outbreak of SARS after the SARS epidemic had been declared over. In fact, the outbreak was caused by OC43, one of the coronaviruses that causes the common cold. https://www.cdc.gov/coronavirus/general-information.htmlSample quote If you are found to be infected with a common cold coronavirus (229E, NL63, OC43, and HKU1) End quote
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Re: The official Coronavirus thread
[Re: 360view]
#2808121
08/12/20 02:51 PM
08/12/20 02:51 PM
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Joined: Jan 2006
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360view
Moparts resident spammer
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Moparts resident spammer
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Re: The official Coronavirus thread
[Re: 360view]
#2808126
08/12/20 03:02 PM
08/12/20 03:02 PM
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Joined: Jan 2006
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Moparts resident spammer
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UC Riverside details how they discover potential medicines for Covid-19 https://medicalxpress.com/news/2020-08-scientists-hundreds-drug-candidates-covid-.htmlSample quote Ray and Kowalewski used their machine learning models to screen more than 10 million commercially available small molecules from a database comprised of 200 million chemicals, and identified the best-in-class hits for the 65 human proteins that interact with SARS-CoV-2 proteins. Taking it a step further, they identified compounds among the hits that are already FDA approved, such as drugs and compounds used in food. They also used the machine learning models to compute toxicity, which helped them reject potentially toxic candidates. This helped them prioritize the chemicals that were predicted to interact with SARS-CoV-2 targets. Their method allowed them to not only identify the highest scoring candidates with significant activity against a single human protein target, but also find a few chemicals that were predicted to inhibit two or more human protein targets. "Compounds I am most excited to pursue are those predicted to be volatile, setting up the unusual possibility of inhaled therapeutics," Ray said. End quote
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Re: The official Coronavirus thread
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#2808491
08/13/20 03:15 PM
08/13/20 03:15 PM
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Joined: Jan 2006
Posts: 8,162 USA
360view
Moparts resident spammer
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Moparts resident spammer
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Re: The official Coronavirus thread
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#2808492
08/13/20 03:16 PM
08/13/20 03:16 PM
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Joined: Jan 2006
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360view
Moparts resident spammer
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Moparts resident spammer
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Re: The official Coronavirus thread
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#2808500
08/13/20 03:26 PM
08/13/20 03:26 PM
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Joined: Jan 2006
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Moparts resident spammer
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Boston MA researchers make an argument that: Covid-19 in New York City over two months in year 2020 was more deadly than Spanish H1N1 influenza was in its worst two months in NYC in year 1918 https://medicalxpress.com/news/2020-08-deadly-yorkerscovid-flu.html( I personally am not convinced)
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