Yes that's what it sounded like to me as well.

Op are you saying that the trans up/down angle is off vs pinion up/down angle or when front u-joint is straight up and down the rear u-joint is rotated a number of degrees clockwise/counterclockwise in relation?

Shouldn't be any -twist- in the shaft.

As for front to back, the angles should cancel out. For example, if trans output is 2deg down, rearend should be 2deg up, then u-joints cancel each other out.

Not uncommon for pinion to be -down- outside this range on a drag car as it will climb the pinion on launch and performance is priority to smoothness.

But, for chasing vibrations, here is a good visual. Don't forget to check centering driver to passenger side also.

https://www.youtube.com/watch?v=Idk3BVDVHq4