We did a 427 inch SB years ago with a Milodon road race pan. The windage tray needed to be heavily modified. Wasn't much left of it by the time it fit.
I got to worse than this with a big block , then just threw it away .
Tex
New best ET 10.259@129.65 . New best MPH 130.32 Finally fitted a solid cam, stepped it up a bit more 3690lbs through the mufflers New World block 3780lbs 10.278@130.80 . Wowser 10.253@130.24 footbraking from 1500rpm Power by Tex's Automotive