For this build, I think it's overkill to go w/ a CCW crank. No downsides other than cost, but I don't think it needs it.

I'd love to hear more on the reasoning not to go over 4.5" stroke by those "people in the know" you referred to earlier.

CHIP
'70 hemicuda, 575" Hemi, 727, Dana 60
'69 road runner, 440-6, 18 spline 4 speed, Dana 60
'71 Demon, 340, low gear 904, 8.75
'73 Chrysler New Yorker, 440, 727, 8.75
'90 Chevy 454SS Silverado, 476" BBC, TH400, 14 bolt
'06 GMC 2500HD LBZ Duramax