In the end, sticking with all Mopar dimension parts in the crank and rods will cost you in both $$ and weight, which a stock block doesn't like. You could keep an eye out for a used after market crank with stock Mopar rod journals, grind it for a 2.2 Rod bearing and have a cost effective stroker, at least for the bottom end.
Personally, I would look for a used 4.15 and go out to 4.25 + with the available 7.1 rod with 2.2 bearings and a .990 piston pin. This gives you 512 cubes, and a fairly light rotating assembly to help the block live. Better yet, if you stumble across a good crank with center counter weights, that is worth a lot of stress off the stock block as well.
If you give us more details of what you intend to use this motor for, and the manners/power level you want, better suggestions can be given.