Well, a carb is quick and easy, and while we haven't seen ¼ mile numbers, hotroddave40 has proven that mileage can be had with a decent little build that's thought out on a carb, and NO OD as of yet. Almost 30 mpg...

It comes down to what would serve the driver best. If I was building a car for my wife or mother, I'd do a 318 pretty much identical to Dave's and be done with it, except maybe the addition of an A-500 or 518.