I've talked to different builders and it seems to be 50/50 on spraying them versus not. Dan Costello (DRAM here, RIP) at Performance Only recommended I spray them, so I did. Never had an issue since 2006. Even after hurting some pistons w/ nitrous, I've never hurt a head gasket. Can't be too detrimental to their performance.
The hemi head gasket gets REAL thin near the pushrod on a big bore too.


CHIP
'70 hemicuda, 575" Hemi, 727, Dana 60
'69 road runner, 440-6, 18 spline 4 speed, Dana 60
'71 Demon, 340, low gear 904, 8.75
'73 Chrysler New Yorker, 440, 727, 8.75
'90 Chevy 454SS Silverado, 476" BBC, TH400, 14 bolt
'06 GMC 2500HD LBZ Duramax