Best to provide a vehicle weight and the goals as there are too many different ways to get there.

For me, I prefer a single turbo, air to air in a street driven vehicle. No turbo/extra maintenance. Only normal "vehicle" maintenance.

The main benefit about a turbo is you can keep gearing/converter/camshaft size down (assuming less than 1,000 hp) making it much more streetable than many other power adders, including N/A builds.