It depends on how you build the engine as well as how you use the car. If you are using it for street use and not drag racing with slicks then the rear end should be fine. You can have the transmission rebuilt with HD parts to handle the extra power. Just have it rebuilt as a Hemi trans and you should be fine.

Heads, cam, intake, etc. choices are all based on how you plan to use the car. For street use you'll want to stay conservative with those parts. Keep the compression down around 10:1, use a hyd flat tappet or hyd roller cam, a dual plane intake, etc.