The closed loop will allow the system to adjust, but for consistency, I would turn it off once the system is dialed in.

Also the availability of built in data loggers, high resolution spark/fuel tables, no more spilled fuel...lol

If you want to get more advanced, you would also have the ability to have temp/pressure dependent timing corrections, i.e. pull timing in good air to run the same number no matter what the conditions are...this would take some track time to dial in, but could be deadly.