I'm running 9.7:1 with a TQ50 Erson cam, flat top KB pistons that are out .009" (oops), ported 452 heads, headers and a torker II intake. All in a 5000lb 4x4. Running a stock distributor with the slots shortened up and the heavy spring removed and, if I remember correctly, 38 degrees total timing. So far I have had zero problems with detonation. Running NGK V-power 7 plugs. I am at 5000 feet in elevation though. I took it to Vegas but had fuel delivery problems so I wasn't exactly hammering on it. It is a 4spd so the load is similar. I do, on occasion, have issues with the plugs fouling slightly at extended low RPM, but they clear up quickly. And by low RPM I mean 600 RPM lugging because I'm too lazy to downshift. Don't know if any of that helps =). I have a set of Stage VI heads I'm porting that will end up on there eventually. Tight quench with a .045" gasket and .009" out should make for a detonation resistant setup in spite of the higher compression. Guess I'll find out.