I had the XE295HL in my 496 with Eddy heads and used the standard Comp Lifters with Crane adjustable rockers. Preload was at 1/3 turn.
No way was there objectionable noise....there was SOME valvetrain noise, but the noise from the piston clearances was a lot worse.
Look at a Comp XEHL cam and then a milder MP cam.....lobe differences???....Yep! The Comps are quite aggressive.