My uncle is redoing the #'s matching 383 to his 1969 4 speed roadrunner. He had to bore it out .030 and is using SpeedPro L2315NF pistons. The original camshaft is no good, so he wants something a little bigger to replace it. Staying with flat tappet hydraulic. Engine will have stock steel heads, HP manifolds, cast intake, but probably go with a 750 carb. Car is strictly a cruiser. Any recommendations on a camshaft that would be a little bigger than stock that would fit the bill? He was thinking something around .480-.500 lift.

The cam should be picked by a cam grinder, since it will need to match the stock manifolds and gear recomendations. IMHO a cam with only maybe two to four degrees more duration than stock, MAYBE a little narrower lobe seperation, and lift a little over stock. Are you using stock rockers? Also ask around about the benidits of some basic bowl work and back cutting valves on those stock heads. Get the right combo and it will out perform the original, yet retain that low speed torque that sold me on a 68 coronet 383 4 speed with 3.23 gears i bought back in 1970!!

Talk to Dwayne Porter (Fast68plymouth). The cam needs to be spec'd to work w/ the manifolds.

Dwayne porter is who you should get a cam from, I will add that with stock exh manifolds do NOT get a narrow LSA cam, you need one with a 112 to 114 LSA , 220 @ .050 in,,230 @ .050 exh , in this area

A friend of mine has a a very similar build with stock heads and manifolds, even a stock carb w/factory A/C and power brakes so good idle quality and vacuum was a must. He ended up using this cam and is very happy.
Hughes Engine

Hughes sells the Hylift USA made lifters so that is a plus right there.

In my experience, with a stock 68 charger R/T with orig 440 w/ 3.23 gear and auto trans. I'm in Denver, so altitude will have some effect. I swapped from the factory cam to a comp XE268 (224/230 @.050, 110 LSA) and lost 2 tenths in the 1/4. Most of which was in the 60'. MPH was the same. My advice to you would be to either put a factory magnum cam in it (214/225 @.050, 115LSA) or something very similar to those specs. Much more duration and/or less LSA will hurt the bottom end performance, which for a street car is the whole name of the game.

Summit cams are decent for stock rebuild

Compression?
Diff gear ratio?
Tire size?

I had different 3rd members for my '69 383 4-speed Super Bee and would swap between 3.23 and 3.91 or 4.10 depending on what I was planning to do w/ the car. Close-to-stock 383s IMO don't have much torque and the longer gears (3.23 - 3.55) are going to suffer more from having too big a cam than 3.91 or 4.10. And the more stock it is, the less "happy" the combination will be if you go too big.

the 383 in my charger has the old racer brown SSH25 cam in it, advanced 4 degrees, the old DP4B intake with the big thermo-quad adapted with a 3/4" spacer, and a set of 1 3/4" headers into a full length 3" exhaust, [possibly hookers, but i don't remember, and the guy i got them from has been gone for years] coupled to a B&M super holeshot converter, going int a 3.91 rear with 29.5 diameter [10.00-15] tires.
car works pretty good for what it is, and being heavy.
lots of fun on the street, and the last time it was at a strip [airport drags] it ran 13.8 something, spinning almost the whole way down the track.
i was contemplating changing out the engine for one i bought off a member here years ago, [446, MP 590 cam, 11:1 compression, performer RPM intake, using my TTI 2"-2 1/8" step headers and another big T-quad] but i decided to use that engine in my 33 dodge "humpback" panel truck "the endless project" instead.

Unless you want a Custom The Crower 267HDP is a great 383 Magnum replacement cam

220/223 @.050 on 112 in at 107

.478/.486 lift

Part number #32241

If you run headers with at least 2500 stall and 3.55 gears, the 271HDP # 32242 is 222/234 @ .050 and .486/.496 same ICL and lobe separation.

Both cams work great, if you cut the 271 on 108 it's a super fun no fuss 383 cam in a B or E body. more punch out of the hole than the .484 in a 383.

383's generally like to be cammed on the street similar to a 340, too much intake duration (specifically the degrees past BDC before closing) and you can kill a lot of bottom end because of the short stroke that you don't necessarily gain back up top.

That 224/228 Hughes looks like it would be a nice grind , probably want to check piston to valve with that advertised lift though.

hopefully I can give you a recommendation as I have built alot of stock appearing and run like a scalded dog. I go back to the same camshaft every time. Its a 1978 Plymouth Fury 440 police interceptor camshaft. I get mine from NAPA. I believe they are manufactured or boxed as Sealed Power.Also a good 650 cfm carb will suffice. Birdtracker