I suspect that study is pure BS. The US is nearing 6 million cases. If that study is representative of the “real world” then we would have over 4 million people suffering “harsh after effects”. We don’t. Not even close, otherwise we would all be VERY AWARE of this issue.

These were not all Covid-19 patients,
but were the smaller number who had severe enough illness to be admitted to this British NHS Hospital.
Something like the sickest 10% to 20%.

Perhaps even less because in the NHS the ER doctors can make the decision to send you home with very little legal ramifications even if you die at home.

Slightly off topic..

Treat a stroke patient with a large blood tranfusion

https://medicalxpress.com/news/2020-08-blood-transfusions-brain.html

Sample quote

Ren's research indicates that blood transfusions can take place beyond that limited window—up to seven hours—and still have a positive impact. Replacing 20 percent of the blood in a mouse was enough to show a profound reduction in damage to the brain. The average adult holds around one-and-a-half gallons of blood in the body.
...snip...
The idea is to change the immune response that happens after stroke," Simpkins said.

Researchers explained that following a stroke, the makeup of a patient's blood changes, causing disruptions in the brain and how the body responds. Neutrophils, a type of white blood cell that helps lead the immune system's response, play a role in increasing the levels of an enzyme called MMP-9, which can lead to blood-brain barrier leakage and degeneration in brain tissue.

Blood replacement therapy removes inflammatory cells and decreases neutrophils and MMP-9 levels following a stroke, the study concluded.

"The immune system doesn't recognize much of what's happening when there's a stroke," Simpkins said. "So the neutrophils go to the brain and try to clean up the damage that happens. But there's too much in the brain and those same neutrophils release MMP-9, which then exacerbates the damage.

End quote

Covid-19 does cause strokes. For every Covid-19 death there may be 2-3 strokes in surviving Covid-19 patients.

Another large study, this time in Italy, matches the earlier Detroit study in the Henry Ford Hospitals, about the use of Hydroxychloroquine.

https://medicalxpress.com/news/2020-08-hydroxychloroquine-in-hospital-covid-mortality.html

Sample quote

An Italian observational study contributes to the ongoing debate regarding the use of hydroxychloroquine in the current pandemic. The research, conducted on 3,451 patients treated in 33 hospitals throughout the Italian territory (list of participating centers attached), shows that the use of this drug reduces by 30% the risk of death in hospitalized patients affected by COVID-19.
...snip...

"We observed—explains Augusto Di Castelnuovo, epidemiologist at the Neuromed Department of Epidemiology and Prevention, currently at Mediterranea Cardiocentro in Naples—that patients treated with hydroxychloroquine had a 30% lower in-hospital mortality rate compared to those not receiving this treatment. Our data were subjected to extremely rigorous statistical analysis, taking into account all the variables and possible confounding factors that could come into play. The drug efficacy was evaluated in various subgroups of patients. The positive results of hydroxychloroquine treatment remained unchanged, especially in those patients showing a more evident inflammatory state at the moment of admission to the hospital."
...snip...
At variance with some studies carried out in other countries, where efficacy of the drug was not observed, it is interesting to note that the doses of hydroxychloroquine adopted in Italy (200 mg, twice a day) are lower than the ones used in those researches."

End quote

Female immune systems counteract Covid-19 better

https://medicalxpress.com/news/2020-08-women-mount-stronger-covid-immune.html

Sample quote

Researchers found that women mounted a more robust immune response involving T lymphocytes, which are a type of white blood cell that can recognize viruses and eliminate them.

This was the case even among older women, the study found.

In contrast, older men had weaker T cell activity—the older they were, the weaker the response.

Overall men also produced more cytokines, which are inflammatory proteins that form another part of the body's natural immune defence.
...snip...
According to the authors, this could imply that men and women need different treatments.

For men, for example "we should be enhancing their T cell responses with vaccines" Iwasaki said,
while women could be given treatment to dampen the cytokine response.

End quote

N95 respirators can be used 3 if decontaminated these 3 ways

https://medicalxpress.com/news/2020-08-single-use-n95-respirators-decontaminated.html

$5 fifteen minute result Covid-19 test from Abbot Labs

https://medicalxpress.com/news/2020-08-rapid-coronavirus-doesnt-specialty-equipment.html

Vitamin C helps retain muscle mass for those past age 50

https://medicalxpress.com/news/2020-08-vitamin-50s-retain-muscle-mass.html



Spouses as a team working together lose more fat than single individual efforts

https://medicalxpress.com/news/2020-08-spouses-pounds.html

Canada running human clinical trial of cat coronavirus antiviral drug

https://medicalxpress.com/news/2020-08-antiviral-cat-coronavirus-sars-cov-.html

LG wearable battery powered HEPA filter mask

https://www.digitaltrends.com/wearables/lgs-new-battery-operated-mask-is-a-wearable-air-purifier/

Sample quote

The PuriCare Wearable Air Purifier can also clean itself with UV-LED lights, so you don’t have to clean it after each use.

End quote

Normally harmless types of stored fat may turn toxic when a Covid-19 infection causes their rapid release

https://www.medpagetoday.com/reading-room/aga/lower-gi/86940

Sample quote

How were you first alerted to the possible connection between UFAs and COVID-19 severity?

Singh: It was the similar patterns between COVID-19, a new disease with no treatment, and pancreatitis, an old disease, which we're currently studying. For example, obesity is a risk factor for both, and multi-organ failure can occur in both, although one disease starts in the lungs and the other in the digestive tract. And in either disease, severity is preceded by hypoalbuminemia and hypocalcemia. In addition, lipase elevation is linked to severity in COVID-19 and also mediates severity in pancreatitis.

The resemblances of the dietary patterns, clinical features, and autopsy findings for severe COVID-19 to those for severe acute pancreatitis were astounding!
...snip...
How are these fats potentially lethal?

Singh: Humans have 1 to 5 kilograms of linoleic acid stored in fat. In this stored form it's safe, but it's released by lipases in pancreatitis and in COVID-19. The lethal dose of linoleic acid is 280 milligrams per kilogram -- just 23 grams for a person weighing 80 kilos. Similarly, in the case of oleic acid, only very low doses are needed for lethality.

Which dietary sources contain high levels of UFAs?

Singh: It's all related to composition based on double bonds in a long fatty acid chain with more than 12 carbons. Linoleic and oleic acid are the two most abundant UFAs in the human body, and linoleic acid has increased to now comprise more than 20% of our stored fat. Commonly consumed vegetable oils such as safflower, sunflower, and corn are all quite high in linoleic acid, while oleic acid makes up a large part of olive, canola, and peanut oil.

End quote

Our future hospital visitor: LaLuchy Robotina

https://medicalxpress.com/news/2020-08-robot-eases-loneliness-mexican-virus.html

Long Wall Street Journal article analyzing how different countries fared with degrees of lockdown.

http://archive.is/cB162

Japanese study says that
blocking Cytokine IL-6 with the monoclonal antibody drug “Actemra”
helps reduce severe Covid-19

https://medicalxpress.com/news/2020-08-antibody-blockade-effective-treatment-severe.html

Sample quote

Strikingly, patients from all three groups had elevated levels of proinflammatory cytokines IL-6, IL-8, IL-10, and MCP-10, as well as a protein called PAI-1, which causes small blood clots in vessels throughout the body, including the lungs.

Importantly, increased PAI-1 levels are associated with more severe cases of pneumonia, a common cause of death among COVID-19 patients.

Because IL-6 was positively associated with the levels of the other cytokines and PAI-1, the researchers concluded that IL-6 signaling is crucial for the development of Cytokine Release Syndrome (CRS) following infection or trauma, and may play a role in the pathogenesis of COVID-19.

"Examination of cytokine profiles in severe COVID-19 patients revealed an increase in IL-6 early in the disease process, causing release of PAI-1 from blood vessels," says study senior author Tadamitsu Kishimoto. "Interestingly, PAI-1 levels were significantly higher in COVID-19 patients with severe respiratory impediment."

Most significantly though, when severe COVID-19 patients were treated with a human monoclonal antibody-based drug called Actemra, which blocks IL-6 signaling, PAI-1 levels rapidly declined and severe disease symptoms were alleviated.

End quote

Government run nursing homes in England did worse fighting Covid-19 spread than
similar facilities in Scotland, Wales or Northern Ireland.

https://medicalxpress.com/news/2020-08-homes-england-greatest-excess-deaths.html

Sample quote

Of all deaths registered as COVID-19 related in the UK,
17,127 (31%) occurred within care homes
and at least 21,775 (40%) were accounted for by care home residents.
...snip...
England is the only UK nation that has released COVID-19 mortality data on those receiving care at home.

End quote

Tele-medicine is probably here to stay in USA healthcare

https://medicalxpress.com/news/2020-08-fad-future-telehealth-expansion-eyed.html

Sample quote

University of Michigan health policy expert Mark Fendrick says
Medicare should figure out what services add value for patients' health and taxpayers' wallets, and pay just for those.

Telehealth "was an overnight sensation," said Fendrick. "Hopefully it's not a one-hit wonder."

End quote

Big study indicates low blood pressure is beneficial, even “normal” is good to reduce

https://medicalxpress.com/news/2020-09-blood-pressure-beneficial-previously-thought.html

Sample quote

This was the largest—and most detailed—study ever conducted to examine these questions. The researchers combined data on individuals who had participated in a randomized clinical trial and conducted a meta-analysis. The study included 348,854 participants from 48 trials.

Participants were divided into two groups: those with a prior diagnosis of cardiovascular disease and those without. Each group was divided into seven subgroups based on systolic blood pressure at study entry (less than 120, 120-129, 130-139, 140-149, 150-159, 160-169, 170 and above mmHg).

Over an average four years of follow-up, each 5 mmHg reduction in systolic blood pressure lowered the relative risk of major cardiovascular events by about 10%. The risks for stroke, ischaemic heart disease, heart failure and death from cardiovascular disease were reduced by 13%, 7% and 14% and 5%, respectively.

End quote

Real world test of N95 mask wearing...

https://medicalxpress.com/news/2020-09-sars-cov-antibodies-percent-frontline-health.html

Sample quote

Persons who reported always wearing a face covering while caring for patients had lower Covid-19 antibody seroprevalence than those who did not (5.6 versus 9.0 percent).

End quote

Google and Apple revising their joint Covid-19 notification system after local Health Departments complained it required too much App support resources from their strained finances

https://www.cnet.com/news/apple-and...re-notifications-ditch-app-requirements/

Plasmin could be the link between COVID-19 comorbidities and serious illness.
Existing drug TXA (tranexamic acid) might treat it.

https://medicalxpress.com/news/2020-09-plasmin-link-covid-comorbidities-illness.html