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Re: The official Coronavirus thread [Re: 360view] #2780565
06/02/20 06:56 AM
06/02/20 06:56 AM
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All I can say is: Yikes!

https://www.sciencemag.org/news/202...s-its-massive-analysis-bat-coronaviruses

Sample quote

There is plenty of evidence that some of these viruses are spilling over to humans all the time in southern China, Daszak says. In an earlier paper, Daszak and co-workers found SARS-related antibodies to coronaviruses in about 3% of people they sampled in China living near bat caves, suggesting they had been infected by some of these viruses. He argues that the world needs to change its approach and go from reacting to pandemics to trying to identify dangerous coronaviruses before they emerge. Many more viruses that are closely related to SARS-CoV-2 are just waiting to be discovered in wildlife, Daszak says. “But, of course, if history repeats itself, by the time we’ve found all the rest of the SARS-2 clade, something else will be emerging.”

End quote

Terrorists are watching all this.

Re: The official Coronavirus thread [Re: 360view] #2780649
06/02/20 11:20 AM
06/02/20 11:20 AM
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Fuzzy info on nicotine patches against COVID-19

https://medicalxpress.com/news/2020-06-nicotine-therapy-coronavirus-evidence-weak.html

Sample quote

The cell receptors that nicotine binds to are ones that SARS-CoV-2 is also thought to affect. Some scientists speculate these links mean nicotine would lead to worse COVID-19 outcomes. Others speculate the opposite. Until tests are done in humans, it's impossible to know for sure.

Early studies in Wales and France are testing nicotine replacement therapy as a potential treatment for COVID-19, and more trials may soon be underway.

It has also been suggested that studies currently testing nicotine replacement therapy for other conditions, such as a US study looking at nicotine replacement for reducing cognitive impairment, could look at COVID-19 outcomes as well.
End quote

Re: The official Coronavirus thread [Re: 360view] #2780650
06/02/20 11:32 AM
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Ancient Australian plant “Benth” (Nicotiana benthamiana ) may help in production of COVID-19 vaccine

https://medicalxpress.com/news/2020-04-ancient-australian-production-covid-vaccine.html

Re: The official Coronavirus thread [Re: 360view] #2780657
06/02/20 11:47 AM
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Over age 50 women drinking even more than men during pandemic in Australia

https://medicalxpress.com/news/2020-06-women-pandemic-lot-mental-health.html

What do Moparts members observe?

Re: The official Coronavirus thread [Re: 360view] #2780818
06/02/20 05:33 PM
06/02/20 05:33 PM
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Originally Posted by 360view
Over age 50 women drinking even more than men during pandemic in Australia

https://medicalxpress.com/news/2020-06-women-pandemic-lot-mental-health.html

What do Moparts members observe?


Not sure if my wife is drinking more or not but I'm doing my best to keep up with her.....lol!! beer

Re: The official Coronavirus thread [Re: 360view] #2780962
06/03/20 06:38 AM
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Wall Street Journal is reporting Eli Lilly Inc. has high hopes that their “monoclonal antibody” to fight COVID-19 can finish human testing soon, go into mass production, and be in use much earlier than the first vaccines.

My guess is that getting a one hour long IV of these monoclonal antibodies will cost anywhere from one to five hundred times more than the cost of getting a traditional vaccine, but the antibodies start working immediately, whereas the vaccine takes 2 to 4 weeks. Good vaccines create both antibodies and T-cells.

Re: The official Coronavirus thread [Re: 360view] #2780991
06/03/20 10:00 AM
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Wall Street Journal is reporting on Friday’s page A9
that a clinical trial is being run at
the University of Toronto
to see if a component of “Fish Oil”,
the Omega-3 oil known by its initials EPA,
and sold in highly purified form
as the Amarin Inc. made prescription drug Vascepa,
can treat COVID-19 Virus
by reducing inflammation and protecting the inner layer of blood vessels known as the Endothelium.

Re: The official Coronavirus thread [Re: 360view] #2781036
06/03/20 12:15 PM
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https://nationalpost.com/news/world/top-epidemiologist-admits-he-got-swedens-covid-19-strategy-wrong

Quote
Top epidemiologist admits he got Sweden's COVID-19 strategy wrong.

At 43 deaths per 100,000, Sweden's mortality rate is among the highest globally and far exceeds that of neighbouring Denmark and Norway

Sweden’s top epidemiologist has admitted his strategy to fight COVID-19 resulted in too many deaths, after persuading his country to avoid a strict lockdown.

What’s more, there’s so far limited evidence that Sweden’s decision to leave much of its society open will support the economy. Finance Minister Magdalena Andersson recently warned that Sweden is facing its worst economic crisis since World War II, with GDP set to slump 7% in 2020, roughly as much as the rest of the EU.


High death rate, and a busted economy? Woops.


If you ever find yourself in a fair fight, your tactics suck.
Re: The official Coronavirus thread [Re: hooziewhatsit] #2781047
06/03/20 12:41 PM
06/03/20 12:41 PM
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That has to be fake, nobody in power ever admits publicly to making a mistake.


When an adversary has the upper hand, just take the cowards way out, ban him.
Re: The official Coronavirus thread [Re: hooziewhatsit] #2781076
06/03/20 02:15 PM
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Previously we were told that
only after most countries reach 60% total recovered and “Herd Immunity” status,
could one particular country tally up its deaths
and then compare itself to other countries total deaths when those countries population reached 60% recovered.

That still sounds right to me.

Sweden is only at about 8% recovered from COVID-19 and has 52% to go.

My guess there is maybe 5 to 15% in every population that is somehow immune to COVID-19.

With the prior AIDS epidemic it took years before it was discovered that some people have the CCR5 DELTA-32 gene variation that makes them immune to HIV.




Re: The official Coronavirus thread [Re: 360view] #2781081
06/03/20 02:27 PM
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Re: The official Coronavirus thread [Re: 360view] #2781088
06/03/20 02:40 PM
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Re: The official Coronavirus thread [Re: 360view] #2781104
06/03/20 03:17 PM
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Men, hormones and COVID-19

https://www.sciencemag.org/news/2020/06/why-coronavirus-hits-men-harder-sex-hormones-offer-clues

Sample quote

But after the Cell paper was published, Andrea Alimonti, head of molecular oncology at Università della Svizzera italiana, strengthened the androgen link by looking at data on more than 42,000 men with prostate cancer in Veneto in Italy. He and colleagues found that patients on androgen-deprivation therapy (ADT)—drugs that slash levels of testosterone—were only one-quarter as likely to contract COVID-19 as men with prostate cancer not on ADT, they reported in the Annals of Oncology. Men on ADT were also less likely to be hospitalized and to die, although numbers were small.

End quote

Re: The official Coronavirus thread [Re: 360view] #2781156
06/03/20 06:00 PM
06/03/20 06:00 PM
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[quote=360view]Previously we were told that
only after most countries reach 60% total recovered and “Herd Immunity” status,
could one particular country tally up its deaths
and then compare itself to other countries total deaths when those countries population reached 60% recovered.

That still sounds right to me.

Sweden is only at about 8% recovered from COVID-19 and has 52% to go.

My guess there is maybe 5 to 15% in every population that is somehow immune to COVID-19.

With the prior AIDS epidemic it took years before it was discovered that some people have the CCR5 DELTA-32 gene variation that makes them immune to HIV.


[

You can pull this back up in a couple of months and hold me to it, but I don’t think we need to get anywhere near 60% infection rate to benefit from herd immunity. I think we will find out that a fairly hefty portion of the population has some level of inherent immunity to coronaviruses. This can be witnessed around the world and particularly in Europe as the infection rate is way down even though most countries have significantly reduced their emergency measures. The bell curve is playing out in virtually every country.

Re: The official Coronavirus thread [Re: dd340] #2781304
06/04/20 08:29 AM
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Originally Posted by dd340
[quote=360view]Previously we were told that
only after most countries reach 60% total recovered and “Herd Immunity” status,
could one particular country tally up its deaths
and then compare itself to other countries total deaths when those countries population reached 60% recovered.

That still sounds right to me.

Sweden is only at about 8% recovered from COVID-19 and has 52% to go.

My guess there is maybe 5 to 15% in every population that is somehow immune to COVID-19.

With the prior AIDS epidemic it took years before it was discovered that some people have the CCR5 DELTA-32 gene variation that makes them immune to HIV.


[

You can pull this back up in a couple of months and hold me to it, but I don’t think we need to get anywhere near 60% infection rate to benefit from herd immunity. I think we will find out that a fairly hefty portion of the population has some level of inherent immunity to coronaviruses. This can be witnessed around the world and particularly in Europe as the infection rate is way down even though most countries have significantly reduced their emergency measures. The bell curve is playing out in virtually every country.


Done, a man of his convictions up


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Re: The official Coronavirus thread [Re: 360view] #2781473
06/04/20 06:33 PM
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2nd larger gene study confirms that
those with Blood Type O slightly protected against severe COVID-19
while Blood Type A more at risk.

https://www.news-medical.net/news/2...ity-to-COVID-19-respiratory-failure.aspx

Re: The official Coronavirus thread [Re: 360view] #2781833
06/05/20 06:10 PM
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cancer drug acalabrutinib,
a BTK protein inhibitor that is approved to treat several blood cancers,
was associated with reduced COVID-19 respiratory distress and a reduction in the overactive immune response in most of the treated patients.

https://medicalxpress.com/news/2020-06-potential-approach-severe-respiratory-distress.html

Sample quote

This prospective off-label clinical study included 19 patients with a confirmed COVID-19 diagnosis that required hospitalization, as well as with low blood-oxygen levels and evidence of inflammation. Of these patients, 11 had been receiving supplemental oxygen for a median of two days, and eight others had been on ventilators for a median of 1.5 (range 1-22) days.

Within one to three days after they began receiving acalabrutinib, the majority of patients in the supplemental oxygen group experienced a substantial drop in inflammation, and their breathing improved. Eight of these 11 patients were able to come off supplemental oxygen and were discharged from the hospital. Although the benefit of acalabrutinib was less dramatic in patients on ventilators, four of the eight patients were able to come off the ventilator, two of whom were eventually discharged. The authors note that the ventilator patient group was extremely clinically diverse and included patients who had been on a ventilator for prolonged periods of time and had major organ dysfunction. Two of the patients in this group died.

End quote

Re: The official Coronavirus thread [Re: 360view] #2781835
06/05/20 06:14 PM
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https://medicalxpress.com/news/2020-06-pets-major-pandemic-stress.html

Sample quote

"If you're feeling down or struggling with your mental health, your pet companion can help," Levine said. "Spend some time with them playing or just petting them. You may find that you feel better, and your pet will love the bonding time, too."

End quote

Re: The official Coronavirus thread [Re: 360view] #2781838
06/05/20 06:20 PM
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Re: The official Coronavirus thread [Re: 360view] #2781842
06/05/20 06:25 PM
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Another small trial of Famotidine (Pepcid AC)

https://medicalxpress.com/news/2020-06-widely-indigestion-drug-curb-covid-.html

Sample quote

The effects were felt within 24 to 48 hours of taking famotidine, and a rigorous clinical trial is now warranted to see if the drug could be an effective treatment for COVID-19, say the researchers.

Famotidine (Pepcid AC) belongs to a class of drugs known as histamine-2 receptor antagonists, which reduce the amount of stomach acid produced. Famotidine can be taken in doses of 20-160 mg, up to four times a day, for the treatment of acid reflux and heartburn.

The researchers report on 10 people (6 men; 4 women) who developed COVID-19 infection, all of whom happened to have been taking famotidine during their illness.

The severity of five cardinal symptoms—cough; shortness of breath; fatigue; headache and loss of taste/smell as well as general unwellness—was measured using a version of a 4-point scale normally applied to assess the severity of cancer symptoms (ECOG PS).

Seven of the patients tested positive for COVID-19, using a swab test; two had antibodies to the infection; and one patient wasn't tested but was diagnosed with the infection by a doctor.

Their ages ranged from 23 to 71 and they had a diverse range of ethnic backgrounds and known risk factors for COVID-19 severity, including high blood pressure and obesity.

All started taking famotidine when they were feeling very poorly with COVID-19, the symptoms of which had been going on from 2 up to 26 days at that point.

The most frequently used dose was 80 mg taken three times a day, with the average treatment period lasting 11 days, but ranging from 5 to 21 days.

All 10 patients said that symptoms quickly improved within 24-48 hours of starting famotidine and had mostly cleared up after 14 days.

Improvement was evident across all symptom categories assessed, but respiratory symptoms, such as cough and shortness of breath, improved more rapidly than systemic symptoms, such as fatigue.

Seven of the patients didn't experience any side effects while on famotidine, and in the three who did, these were mild, and all but temporary forgetfulness were known side effects associated with taking the drug.

End quote

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