How important is it to you to run E85? I think E85 is great for a boosted street driven car with restrictions on boost but this sounds like 100% race car. Just go straight to Methanol. Race car, race fuel. Put it at 12:1 compression and call someone like Bullet for the cam. I have a much smaller blower on a 405 cubic inch engine and it makes 11 psi on the brake and 38 psi by the 60 foot clocks. Making power won't be the problem for you. Managing it will.