I remember David's comment and essentially I agree, but as an engine builder/tuner I have learned (to a much lesser extent) that there are certain cam tuning specifics you can utilize based on the shortblock configuration and the headflow characteristics that can either enhance the powerband or, if poorly chosen, leave power "on the table". In that regard the rod length can come into play particularly with the intake closing event and maximizing piston velocity past top dead center.

And longevity (specifically side loading which obviously effects both friction and ring seal) is also a factor.