I have a 15 2500 4x4 regular cab long box with the 5.7 Hemi and 242,000 miles with over half towing a 24' enclosed and I have been very happy with the performance of the engine. Typical broken exhaust manifold studs that I hope they have finally fixed. My water pump went out at 239K miles but my lifetime powertrain warranty took care of that with the $200 deductible. No other engine issues and the 68RFE trans has been amazingly strong although I have an engine code for "overunning torque converter clutch" that comes and goes and has been for the last 90K miles. I slips a bit on gear changes but hasn't changed at all in those miles, so I haven't done anything about it yet. They don't offer the 5.7 in a 2500 anymore.