The rocker arm ratio has a lot to do with how the motor reacts to any change in the valve train, especially lift and duration off of the seats
I ended up with Isky RR602 solid roller lifter grind for wedges that had the slowest opening ramps I have ever seen when degreeing that cam, it was horribly slow getting to .050 lifter rise, HORRIBLY slow
It ran fine in all three motors that I had installed it in but it was not as fast in the 60 Ft. times or on the top end MPH in the 1/4 mile with better cams in the same motors
Don't forget that a lot of cam development was done way before computer where use for that function, a lot different technology back then
I think Mark Heffengton was one of the first, if not the first, to use modern technology in designing solid roller drag race cam lobes back in the early 1970s