The chemical of concern in antifreeze is ethylene glycol. Hand sanitizers, which are either ethanol- or isopropanol-based, do not contain ethylene glycol. It is true that ethylene glycol is very dangerous to pets (and humans) if ingested, even in small quantities, but such a fact is irrelevant to the issue at hand.

Although ethanol poisoning (i.e what happens when a human drinks a medically dangerous amount of alcohol) is possible if a pet were to consume large quantities of hand sanitizer, an animal merely licking a recently sanitized hand is not cause for concern. For that reason, the claim is “False.”