Hasn’t this already been discussed?

https://board.moparts.org/ubbthread...tio-and-choose-a-piston.html#Post2716798

One of my customers does this type of build pretty often.
In fact there is another one in the works right now.

Imo, the “right” way to go about it with open chamber heads is use the quench dome pistons.
Then you can use any cam that’s suitable for the application without trying to use it as a crutch to keep the motor from pinging.

Or, get closed chamber heads and pistons that will end up within .040-.050 piston to head clearance.