I don't see a raised cam being a doable thing, especially with an aluminum rod. But never tried it honestly...

FWIW the low deck in my Cuda was only a 4" stroke 525" deal and it ran pretty well. I don't think 4.5" is something most should do, but it can be done. I honestly would likely do a 540" deal with a STD cam block. It is a good combo and will require nothing "unusual" for the combo and should run well