Not going to pick up much running pump gas unless you either decide to run more compression and change camshaft, etc that will allow you to take advantage.
Or change heads to like an indy which will require different rockers, headers, etc, and thus a good bit more money to do so.
Or nitrous
To give you an example, years ago i had an eddie headed 416 that i drove everywhere that ran 10.74 best. Flat tappet motor
Did nothing but change to W5 heads, headers, and intake. Car went 10.38 best. Probably would have went 10.20’s at that point swapping to a roller as well.
But the head, header, rocker gear, intake swapping was well over 5k for the 3.5 tenths gain.
I suspect a swap to Indy heads would be similar. My existing cam that was in both combos was 260/266 600 ish lift.
So those 3 or 4 tenths will cost a bunch. That said selling your topend like i did would offset a good bit of the cost